Disease models used for gastroenterology research are essential tools for understanding the pathophysiology of GI disorders, testing potential therapies, and driving forward clinical applications. Common models include in vitro models (cell culture models, organoids) and animal models (rat, mouse, non-human primates, etc.). In vitro models are used for studying cellular and molecular mechanisms of GI diseases like IBD, colorectal cancer, and infectious enteropathies. Animal models can provide insights into disease mechanisms and preclinical drug testing.
As a leading gastroenterology CRO, Ace Therapeutics provides tailored preclinical gastrointestinal disease models (such as custom appendicitis models) using CRISPR genome editing, microbiome engineering, and rodent surgery for fast-track disease discovery and drug discovery. To be more specific, Ace Therapeutics’ disease models mimic human GI pathophysiology with unprecedented accuracy, incorporating organoids and multi-omics data integration. This enables researchers to study disease progression and therapeutic responses in a controlled, scalable environment.
In addition, Ace Therapeutics’ disease models are suitable for comprehensive coverage of GI disorders. From ulcerative colitis and Crohn’s disease to non-alcoholic steatohepatitis (NASH) and gastric cancer, Ace Therapeutics offers an extensive portfolio. Each model incorporates key pathological features, such as immune dysregulation, microbiome interactions, and tissue fibrosis, enabling multi-target drug testing.
Leveraging advanced gene-editing, organoid cultures, and AI-driven data analytics, the models from Ace Therapeutics allow for personalized research approaches. Whether investigating novel biologics, small molecules, or microbiome-based therapies, researchers can tailor studies to specific mechanisms of interest. Furthermore, by minimizing variability and enhancing reliability, Ace Therapeutics can help shorten preclinical timelines and reduce R&D costs. Pharmaceutical companies and academic labs alike can expedite breakthroughs while optimizing resource allocation.
With a proven track record in gastroenterology research, Ace Therapeutics is the preferred gastroenterology CRO for biopharma innovators. Whether researchers are developing anti-fibrotic therapies, metabolic modulators, or oncology drugs, Ace Therapeutics’ gastrointestinal and liver disease models deliver the robust preclinical data they need.
